Elisabeth (Liz) Rebboah
Postdoctoral Scholar | RNA Enthusiast
San Diego, CA | erebboah@gmail.com
About Me
Computational biologist with a background in experimental assay development, specializing in large-scale single-cell and multi-omic data.
Research Interests
- NGS assay development
- Characterization of transcriptional regulation across cell types and cell states
- Multi-omics data integration
Education
PhD in Computational Biology, UC Irvine (2024)
BS in Bioengineering, UC San Diego (2015)
IGVF Project: Characterization of gene expression variation across Collaborative Cross founder strains
Exploring the impact of genotype on gene expression across 8 core tissues using snRNA-seq. Findings include expansion of immune cell subtypes in key metabolic tissues of a well-characterized diabetes-prone strain (NZO) as well as early detection of transcriptional over-activation in skeletal muscle stem cells of a mouse strain (A) known to develop muscular dystrophy.
Link to paper (placeholder) | Public datasets (placeholder)
ENCODE Project: Mouse postnatal development at the single-cell level
Contributed to ENCODE with half a million snRNA-seq nuclei, building foundational resources for developmental single-nucleus atlases across 5 core tissues. Identified key drivers of transcriptional programs in dynamic and sex-specific cell types by integrating gene expression with open chromatin signatures.
Link to paper (placeholder) | Public datasets (placeholder)
Spatial transcriptomics in mouse hypothalamus & pituitary
Current focus: Characterization of cell types and states in key brain tissues with multiplexed FISH (MERFISH) integration with whole-transcritome single-cell data.